Welcome To BIOPOP

     The laboratory of bioinformatics and population genetics in Seoul National University focuses on producing fundamental material from scattered sources and gathering advanced information related to cancer or disease, approached by all-inclusive studies of informatics, mathematics, statistics, and natural sciences. As a variety of livestock genomes are emerging, by applying the principle of population genetics on domestication genes and analyzing genome polymorphisms, we aim to introduce a new paradigm of genetic breeding.

Lab. News



Received: April 18, 2016 / Accepted: August 31, 2016 /
Published online: September 23, 2016
Scientific Reports. 2016.

Gut microbiota Modulated by Probiotics and Garcinia cambogia Extract Correlate with Weight Gain and Adipocyte Sizes in High Fat-Fed Mice. Jaeyoung Heo, Minseok Seo, Hwanhee Park, Woon Kyu Lee, Le Luo Guan, Joon Yoon, Kelsey Caetano-Anolles, Hyeonju Ahn, Se-Young Kim, Yoon-Mo Kang, Seoae Cho, and Heebal Kim. [LINK]




Accepted Nucleic Acids Resear

Received: July 07, 2016 / Accepted: April 08, 2016 /
Published online: April 29, 2016
Scientific Reports. 2016.

Evolutionary constraints over microsatellite abundance in larger mammals as a potential mechanism against carcinogenic burden. Jung Youn Park, Yong-Rock An, Chul-Min An, Jung-Ha Kang, Eun Mi Kim, Heebal Kim, Seoae Cho & Jaemin Kim. [LINK]




Accepted Nucleic Acids Resear

Received: December 11, 2015 / Accepted: March 22, 2016 /
Published online: April 13, 2016
Scientific Reports. 2016.

RNA-seq analysis for detecting quantitative trait-associated genes. Minseok Seo, Kwondo Kim, Joon Yoon, Jin Young Jeong, Hyun-Jeong Lee, Seoae Cho & Heebal Kim. [LINK]




Accepted Nucleic Acids Research

Received: August 11, 2015 / Accepted: November 1, 2015 /
Published online: Novermber 17, 2015
Nucl. Acids Res. 2015.

HGTree: database of horizontally transferred genes determined by tree reconciliation Hyeonsoo Jeong, Samsun Sung, Taehyung Kwon, Minseok Seo, Kelsey Caetano-Anolles, Sang Ho Choi, Seoae Cho, Arshan Nasir and Heebal Kim [LINK]




Accepted Nature Genetics

Received: January 27, 2014 / Accepted: November 6, 2014 /
Published : December 12, 2014
Science 2014.

Comparative genomics reveals insights into avian genome evolution and adaptation. Guojie Zhang,Cai Li, Qiye Li, Bo Li, Denis M. Larkin, Chul Lee, Jay F. Storz, Agostinho Antunes, Matthew J. Greenwold, Robert W. Meredith, Anders Odeen, Jie Cui, Qi Zhou, Luohao Xu, Hailin Pan, Zongji Wang, Lijun Jin, Pei Zhang, Haofu Hu, Wei Yang, Jiang Hu, Jin Xiao, Zhikai Yang, Yang Liu, Qiaolin Xie, Hao Yu, Jinmin Lian, Ping Wen, Fang Zhang, Hui Li,...., John Gatesy, Federico G. Hoffmann, Juan C. Opazo, Olle Hastad, Roger H. Sawyer, Heebal Kim, Kyu-Won Kim, Hyeon Jeong Kim, Seoae Cho, Ning Li, Yinhua Huang, Michael W. Bruford,...., Huanming Yang, Jian Wang, Avian Genome Consortium,¡× Erich D. Jarvis, M. Thomas P. Gilbert, JunWang [LINK]




Accepted Nature Genetics

Received: December 16, 2012 / Accepted: May 8, 2013 /
Published online: June 9, 2013
Nature Genetics 2013.

The duck genome and transcriptome provide insight into an avian influenza virus reservoir species. Yinhua Huang, Yingrui Li, David W Burt, Hualan Chen, Yong Zhang, Wubin Qian, Heebal Kim, Shangquan Gan, Yiqiang Zhao, Jianwen Li, Kang Yi, Huapeng Feng, Pengyang Zhu, Bo Li, Qiuyue Liu, Suan Fairley, Katharine E Magor, Zhenlin Du, Xiaoxiang Hu, Laurie Goodman, Hakim Tafer, Alain Vignal, Taeheon Lee, Kyu-Won Kim, Zheya Sheng, Yang An, Steve Searle, Javier Herrero, Martien A M Groenen, ..., Frederique Pitel, Jun Wang & Ning Li. [LINK]


Accepted DNA Research

Received: October 8, 2012 / Accepted: March 12, 2013 /
First published online: April 11, 2013
DNA Research 2013.

Peeling Back the Evolutionary Layers of Molecular Mechanisms Responsive to Exercise-Stress in the Skeletal Muscle of the Racing Horse. Hyeongmin Kim, Taeheon Lee, WonCheoul Park, Jin Woo Lee, Jaemin Kim, Bo-Young Lee, Hyeonju Ahn, Sunjin Moon, Seoae Cho, Kyoung-Tag Do, Heui-Soo Kim, Hak-Kyo Lee, Chang-Kyu Lee, Hong-Sik Kong, Young-Mok Yang, Jongsun Park, Hak-Min Kim, Byung Chul Kim, Seungwoo Hwang, Jong Bhak, Dave Burt, Kyoung-Do Park, Byung-Wook Cho, and Heebal Kim [LINK]


Accepted PLoS Genetics

Received: October 2, 2012 / Accepted: January 15, 2013 /
Published: March 7, 2013
PLoS Genetics 2013.

Ubiquitous polygenicity of human complex traits: genome-wide analysis of 49 traits in Koreans. Jian Yang, Taeheon Lee, Jaemin Kim, Myeong-Chan Cho, Bok-Ghee Han, Jong-Young Lee, Hyun-Jeong Lee, Seoae Cho and Heebal Kim [LINK]


Accepted Nature

Received: June 16, 2012 / Accepted: September 27, 2012 / Published online: November 14, 2012
Nature 2012.

Analyses of pig genomes provide insight into porcine demography and evolution Martien A. M. Groenen, Alan L. Archibald, Hirohide Uenishi, Christopher K. Tuggle, Yasuhiro Takeuchi, Max F. Rothschild, Claire Rogel-Gaillard, Chankyu Park, Denis Milan, Hendrik-Jan Megens, Shengting Li, Denis M. Larkin, Heebal Kim, Laurent A. F. Frantz, Mario Caccamo, Hyeonju Ahn et al. [LINK]